Principal Scientist, Imaging AI

Company: Disability Solutions
Location: Cambridge
Posted on: November 1, 2024

Job Description:

Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: .When you join BMS, you are joining a diverse, high-achieving team united by a common mission. The Informatics and Predictive Sciences (IPS) mission is to Pioneer, Partner and Predict to drive transformative insights for patient benefit. IPS conducts applied computational research in areas that include genomic, structural and molecular informatics, computational and systems biology, patient selection and translational biomarker research, and broader fields including knowledge science, epidemiology and machine learning-across the full lifecycle of drug discovery and development and across all therapeutic areas at BMS. We do this in close partnership with scientific and clinical experts in the field, both inside and outside the company." We perform innovative science to empower key data-driven decisions across a rich pipeline of next-generation medicines. In doing so, our work transforms the lives of patients, as well as our own lives and careers.Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You'll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.We are seeking a highly motivated scientist to join our Imaging AI team in the Informatics and Predictive Sciences (IPS) organization. Imaging AI is responsible for advancing Bristol Myers Squibb's industry-leading pipeline through development and application of cutting-edge tissue-based image analysis approaches, often in multi-modal context. We collaborate with a broad range of stakeholders including clinical trial scientists, pathologists, computational biologists, and software engineers.In this role, the applicant will identify and implement strategies of analyzing digital pathology slides using a diverse set of deep learning-enabled workflows: semantic segmentation, instance segmentation, graph neural networks, etc. There will also be close collaboration with colleagues in Applied Machine Learning to build out cutting-edge AI methods that extend our capabilities: weakly supervised multi-instance learning (MIL), foundational models, etc. The successful candidate will be comfortable evaluating a given project and knowing when to utilize off-the-shelf image analysis platform solutions versus custom developed solutions.In addition, the successful candidate will contribute to the data and compute infrastructure around imaging research, in close alignment with IT and other stakeholders. This includes high-performance compute, commercial tools and platforms as well as data and annotation management systems.Responsibilities

• Hands-on implementation and use of pathology whole slide image analysis tools and technology
• Collaboratively devise and execute research strategies that drive decision making in pre-clinical and clinical programs
• Work alongside imaging scientists to manage, prepare and analyze pathology whole slide images to support translational research across multiple disease/therapeutic areas including oncology, immunology, and neuroscience.
• Active participation in identifying, testing and enabling use of pathology image management and analysis systems, tools, and technology.
• Coordinate stakeholders, guide/supervise junior researchers, often in a matrixed setting
• Prepare and present findings from image analysis projects to other groups within BMS and externally at conferences/workshops.Basic Qualifications:
  • Bachelor's Degree 8+ years of academic / industry experience
  • Or Master's Degree 6+ years of academic / industry experience
  • Or PhD 4+ years of academic / industry experiencePreferred Qualifications:
    • Ph.D. in Biomedical Engineering, Computer Science, Bioinformatics, or related discipline; or M.S. with 3 or more years of related experience in a university pathology lab or pharmaceutical or biotech company.
    • Proficiency in programming languages (Python, R, etc.) and data analysis tools (Jupyter Notebooks, Pandas, RStudio, etc.).
    • Preferred: Experience with one or more digital pathology analysis software packages; including HALO, Visiopharm, QuPath and/or other image analysis platforms.
    • Experience with high-performance & cloud computing, container strategies (e.g. Docker), developer tools and machine learning lifecycle management tools highly valued
    • Prior experience in developing deep-learning based image analysis workflows for hematoxylin & eosin (H&E), chromogenic immunochemistry (IHC), and multiplexed immunofluorescence (mIF) images preferred
    • Strong problem-solving and collaboration skills, and rigorous and creative thinking.
    • Excellent written and oral communication skills, including an ability to collaborate effectively with lab scientists and pathologists.
    • Ability to work both independently and collaboratively, and to handle several concurrent, fast-paced projects.
    • Track record of scientific leadership exemplified by peer-reviewed publications, ideally related to pathology image analysis.This is an on-site position, with flexibility of 50% remote work, based at any of BMS' research sites: Cambridge (MA), Lawrenceville (NJ), Seattle (WA), San Diego (CA) or Brisbane (CA)The starting compensation for this job is a range from $129,000 to $177,100, plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final , individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Career Site. Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program. #LI-HybridIf you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Uniquely Interesting Work, Life-changing CareersWith a single vision as inspiring as Transforming patients' lives through science--- , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site Protocol BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role: Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function. BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to . Visit to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Keywords: Disability Solutions, Marthas Vineyard , Principal Scientist, Imaging AI, Education / Teaching , Cambridge, Massachusetts